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Docosahexaenoic Acid methyl ester

CAS No. 2566-90-7

Docosahexaenoic Acid methyl ester( Methyl docosahexaenoate | all cis-DHA methyl ester )

Catalog No. M27071 CAS No. 2566-90-7

Methyl docosahexaenoate is a methylated docosahexaenoic acid analog that can be inserted into membrane phospholipids without being oxidized or hydrolyzed.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Docosahexaenoic Acid methyl ester
  • Note
    Research use only, not for human use.
  • Brief Description
    Methyl docosahexaenoate is a methylated docosahexaenoic acid analog that can be inserted into membrane phospholipids without being oxidized or hydrolyzed.
  • Description
    Methyl docosahexaenoate is a methylated docosahexaenoic acid analog that can be inserted into membrane phospholipids without being oxidized or hydrolyzed.
  • In Vitro
    Sharp wave (SPW) incidence relative to baseline appears to decrease following Docosahexaenoic Acid methyl ester (DHA-Me) application. There is no generation of a new protein band when bovine serum albumin (BSA) is exposed to the Fe2+ and ascorbic acid (AsA) mixed-function oxidation system in the absence of Docosahexaenoic Acid methyl ester (DHA). However, the high-molecular-weight protein band is observed after only 24 h when BSA is incubated with DHA. Incubation of BSA with 1.0 mM DHA leads to a substantial increase in protein carbonyl content and the addition of oxygen radical scavengers leads to a substantial decrease in protein carbonyl content.
  • In Vivo
    ——
  • Synonyms
    Methyl docosahexaenoate | all cis-DHA methyl ester
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    p38α| p38β| TNF-α
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2566-90-7
  • Formula Weight
    342.523
  • Molecular Formula
    C23H34O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?Ethanol : 100 mg/mL (291.96 m)
  • SMILES
    CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCC(=O)OC
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.R?hm S, et al. Fast Iterative Synthetic Approach toward Identification of Novel Highly Selective p38 MAP Kinase Inhibitors. J Med Chem. 2019 Dec 12;62(23):10757-10782.
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